从转基因烟草中提取抗艾滋病药物

From transgenic tobacco extract anti-AIDS drugs

"Great Wall Online" 2009-5-20 PM 01:40:04

     British and American scientists developed a griffithsin to the accumulation of higher protein content (GRFT) of transgenic tobacco. Even in the concentration range皮摩尔level, this protein also on the human immunodeficiency virus (HIV) have a significant inhibitory effect. Protein was first Griffithsin kainic from isolated Griffithsia extracted, it can with the HIV envelope glycoprotein joint, thereby preventing cell-to-cell spread of the HIV virus.

     At present, scientists in the greenhouse of 460 square meters of production Nicotana benthamiana using griffithsin protein 60 grams. They estimated that the output can be produced about one million copies of anti-HIV agents. At present, other anti-retroviral drugs are still expensive-scale production.

     The study found that tobacco griffithsin can effectively inhibit A, B, C three types of HIV virus. A-and C-type HIV virus prevalent in sub-Saharan Africa and the Indian subcontinent region urgently in need of such fungicides. Compared with other fungicides, GFRT also has one of the advantages, it will not stimulate lymphocyte proliferation.
(Article Source: Chinese Red Ribbon Network - International agricultural biotechnology weekly) (Editor:张丽敬)