艾滋病疫苗研究现曙光
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http://www.qhnews.com 新華網2010-05-05 09:39
新發現的兩種抗體可以抵禦以任何形態出現的HIV病毒
據英國媒體報導,艾滋病疫苗研究近日出現重大突破——科學家找到了艾滋病病毒的“阿喀琉斯之踵”。科學家稱,兩種可以攻擊HIV病毒多種毒株的薄弱環節的新抗體被發現,這一發現大大提高了艾滋病疫苗研製成功的希望。
這兩種抗體分別被命名為PG9 和PG16,是科學家在研究取自逾1800名攜帶HIV病毒的志願者的血樣後獲得的。科學家對他們的血樣進行甄別,從中尋找具備廣泛中和能力的艾滋病病毒抗體。
能抵禦任何形態HIV病毒
人類迄今都未研製出可行的艾滋病疫苗。這兩種新抗體的發現之所以重要,是因為HIV病毒很容易發生變異,而這兩種新抗體可以抵禦以任何形態出現的HIV病毒。如果人類研製出一種刺激這兩種抗體產生的疫苗,那麼將能夠有效抗擊HIV病毒。
目前,發現這兩種抗體的國際艾滋病疫苗組織(IAVI)的科學家已經開始著手進一步研究這兩種抗體,從中尋找疫苗設計的線索。與此同時,科學家認為,用於發現這兩種抗體的新技術也為其他方面的進展帶來希望,因為利用新技術很可能揭示艾滋病病毒的其他薄弱之處,從而在研製疫苗時“一網打盡” 。
“我們已經得到了一種對付HIV病毒全新的更好的方式,可以集中精力用於疫苗的設計。”IAVI副總裁韋恩·考夫表示,“有了這個新發現後,我們會乘勝追擊,加速艾滋病疫苗的研製。”
可有效對付多種毒株
同時,PG9 和PG16還可以有效地對付HIV病毒的多種毒株,包括來自艾滋病蔓延最嚴重的非洲的毒株。 (如嘉)
編輯: 王海蓮
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AIDS vaccine research Xian Shuguang
http://www.qhnews.com Xinhuanet 2010-05-05 09:39
Two newly discovered antibodies can arise against any form of HIV virus
According to British media reports, HIV vaccine research has significant breakthrough - Scientists have found HIV in the "Achilles heel." Scientists say the two can attack a variety of strains of HIV, the weak link of the new antibody was found, the discovery of AIDS vaccine development has greatly enhanced the success of hope.
Both antibodies were named PG9 and PG16, a scientist in the research from more than 1,800 volunteers carrying HIV virus after blood samples obtained. Scientists on their blood samples screened from a wide range of search and the ability to have the HIV antibody.
HIV virus can withstand any form
So far none of the human AIDS vaccine developed feasible. These two new antibody discovery is important because the HIV virus is prone to mutation, and two new antibodies appear to resist any form of HIV. If human beings developed a stimulating antibody production of both vaccines, it will be able to effectively fight HIV.
Currently, the two antibodies was found in international AIDS vaccine organization (IAVI), scientists have begun to further study the two antibodies from the vaccine designed to find clues. At the same time, scientists believe, the two antibodies used to detect the new technology's progress Yewei other Fangmian hope, because the use of new technology is likely to Jieshi AIDS virus in the Qi Ta weaknesses, so when Zai Yan Zhi vaccine "Clean Sweep" .
"We've got a better deal with HIV, a new way, can concentrate for vaccine design." IAVI Vice President Wayne Kauf said, "With this new discovery, we will win the accelerate AIDS vaccine. "
Can effectively deal with a variety of strains
Meanwhile, PG9 and PG16 can also be effective against multiple HIV viral strains, including those from the spread of AIDS in Africa, the most severe strain. (Eg, Ka)
Editor: Wang Hailian